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Contraindicated (1)pentobarbital will reduce the level or impact of cariprazine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. CYP3A4 is liable for the development and elimination of cariprazine's Lively metabolites.pentobarbital will reduce the extent or result of aripiprazole by impacting hepatic/intestinal enzyme CYP3
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